Nkarta, a biopharmaceutical company that engineers natural killer cell therapies to treat cancer, announced that two of its therapies have shown complete remission in patients with blood cancer. The exciting results from the Phase I studies are some of the latest hopeful developments in the biopharma space for difficult-to-treat blood cancers.
San Francisco-based Nkarta develops therapies in the oncology space, including for blood cancers. The company has two leading candidates, drugs NKX101 and NKX019.
In a Phase I clinical trial, Nkarta tested NKX101 on patients with relapsed or refractory acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). Because of the difficulty of treating AML, there is currently no standard of care. Nkarta received Orphan Drug Designation from the U.S. Food and Drug Administration for NKX101 in December 2021.
“Relapsed/refractory acute myeloid leukemia (AML) is a historically hard-to-treat disease, and given the lack of effective treatments, people with cancer and those who treat them are faced with few options,” Marcello Rotta, M.D., who works at the Colorado Blood Cancer Institute and was an investigator in the NKX101 clinical trial, said in a statement.
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